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A team of researchers at Harvard’s Wyss Institute and the University of Massachusetts’ New England Center for Stroke Research, has developed a new method that quickly dissolves life-threatening blood clots that completely obstruct blood vessels in stroke patients’ brains.
In clinically relevant large-animal studies, by combining an injectable clot-busting nanotherapeutic (that targets blockages) with an intra-arterial device (that restores blood flow to obstructed vessels), the researchers could dissolve clots that fully blocked brain blood vessels.
Blood Clot TreatmentScientists have developed a new way to treat blood clots.
Posted by Hashem Al-Ghaili on Tuesday, February 16, 2016
According to the Harvard Gazette:
The new advance uses a stent not to drag out the clot, but to create a narrow channel restoring blood flow through an opening in the center of the vascular blockage. Doing so creates a high level of shear force generated by restored flow, activating the nanotherapeutic to release and target the clot-busting drug along the opened channel in the clot. After the blood clot is fully dissolved, the stent is re-sheathed and harmlessly removed from the vessel. If during the process any clot fragments break off and travel through the circulatory system, the drug-coated nanoparticles will remain bound to them and continue to dissolve them locally wherever they go.
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