How To Create Homemade Penicillin. Seriously.


This information I feel is very relevant to potentially everyone but specifically those whom may be living in poverty or have limited resources around the world. Oranges and simple bread are two of the most universally common household kitchen items. But did you know that oranges and bread are capable of producing penicillin simply by letting letting them sit around and age? Believe it or not, that green disgusting mold which develops on the surface of bread is actually called Penicillium.

It is time for a thought experiment: You are living in the middle of the zombie apocalypse. In a dash your partner has deeply slashed their leg. As you take shelter the next few days your partner begins to develop a noticeable infection. Keeping in mind that in real world cases infections can result in serious medical concerns, loss of a limb or death if left untreated, without access to modern medical supplies would you know what to do to help your partner? Here is one cheap and easy way to potentially save your partner from these fates.

  • Take bread and place it in a bag or container
  • Let sit until spores begin to form
  • Take all the bread and break it up into smaller pieces
  • Add some moisture (light misting) and place the broken up pieces back in the same sealed bag or container
  • Monitor the mold growth and do not remove until the majority of the mold culture begins to turn decidedly green.
Google Images: Penicillium Mold. From

As the mold begins to grow and develop it will take on white, blue and green stages. The green mold you see in the picture above illustrates this point. The green color is going to contain doses of penicillin. As you can see the green areas are where the mold has grown the largest, essentially where it has matured. Now that you have this green mold, you can actually begin to use it as treatment. There are a few ways to go about this.

Option A: Take the bread clumps, fill up a large cup full of them and add warm water (not boiling water). Mix together and consume. Repeat as necessary, essentially as daily doses of penicillin. It is important to note that while you are growing the mold, you are most likely growing other things. Not all of the helpful. And when you consume the bread will be getting both penicillin and that bad stuff. Yes, it will also taste terrible. Does the bad outweigh the good? In the scenario above, diarrhea or upset stomach are much less serious problems compared to a major infection. So it can be worth it. This remedy have been used for thousands of year in ancient cultures and has also been seen in many folk remedies around the United States for centuries.

Option B: Take your time and carefully separate nothing but the green mold from the bread. Clean the wound, take your ‘scrapings’  from the bread and topically apply them over the whole would. Dress lightly and repeat this process regularly.

An interesting fact I once learned studying Egyptology. Dating back to Imhotep, ancient doctors used to dress woulds with honey. Why is this? It is actually extremely hard for bacteria to grow on honey. If a wound is fresh and clean and infection free, you can apply honey to the area to preserve it from harmful bacteria. Believe it or not, medical grade honey bandages are still used in modern emergency rooms to this day. For home use simply cover the entire area in honey, and wrap the wound to both keep the honey in place and everything else away.

There are of course more advanced ways to make penicillin from bread and oranges that go beyond what I mentioned above. Perhaps if you have more time, more resources available at hand, you can indeed create potentially pharmaceutical grade penicillin using the same basic process I mentioned above. With the relatively low cost and the wide availability of penicillin in the healthcare marketplace today, this may not be practical. But find yourself in the middle of the zombie apocalypse, this information might just save your life. If you wish to know more advanced means of processing penicillium I recommend reading up on it further.

These statements have not been approved by the FDA.


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    • If you are allergic to penicillin you will most likely be allergic to some degree to many other betalactamic antibiotics.
      I would try the honey approach.

    • If your allergic to penicillin your going to react to amoxicillin too. This whole article is rubbish unless you really are going to die of an infection and your incapable of seeking professional medical treatment. In which case what do you have to lose. What this guy fails to explain is how bacteria are resistant or susceptible to certain antibiotics. Penicillin based antibiotics is great for most gram positive strains but do absolutely nothing for gram negative strains. Their are even more types of bacteria that react differently to all kinds if antibiotics. I cringed when I read this article because if people are actually trying this at home to avoid a doctor visit they are making a HUGE mistake. If you don’t luck out and get a gram positive bacteria or even worse have a resistant super bug strain like Multidrug resistant staphylococcus areus (aka MRSA) you aren’t going to treat it and if you injested that home grown penicillin you very well could kill off your bodies normal flora (good bacteria) and make yourself even sicker. Just stay away from this science project unless you really have no other option.

      • Am am allergic to penicillin, yet I can use amoxicillin without any issues and I know for a fact that it is (or was anyway) used as a replacement for penicillin.

        • You are wrong and just by saying that you know that for fact you are not gonna be right. When somebody shows any symptoms of allergy on penicillin, they are treated with completely different group of antibiotics, e.g. macrolides. ( not very reliable source but there’s a slight chance that you might understand at least wikipedia : “The antimicrobial spectrum of macrolides is slightly wider than that of penicillin, and, therefore, macrolides are a common substitute for patients with a penicillin allergy.)

        • Hey, deathly allergic to penicillin and all derivatives. Your doctor is a dumbass if he/she gives you anything related to it. Every time you are exposed to penicillin or its derivatives, your risk of anaphylaxis increases. I personally have been give the least reative derivative twice. First time, I was totally fine. Second time, I had hives for 3 weeks. If you are allergic to penicillin DO NOT take it’s derivatives.

    • If you have a wound use honey. I would go the propolis route, if you are near bee keepers, or a health food store sometimes has it. Propolis is a very strong antibiotic deposited by bees around the opening of the nursery in the hive to protect it from viruses etc. it’s not very expensive and can be taken orally very safely, or used in extract form to
      bathe wounds, as a mouth rinse, etc. The Russians studied it for years to see if they could manufacture penicillin from it.

        • Honey is antibacterial. It’s proven to be the only food source that never expires. Why because bees dehydrate honey to about 14% mouisture in which bacteria needs atleast 21% to grow. In all cases of infection when you cannot seek trained medical help so to speak use honey the way he said without sealing it off. Proplis is antibacterial as wel yet it is a plant resisn and easily harvested by humans as well if you know how to harvest it. Honey is the best thing in this “situation”. For burns cuts scraps herpes bumps bites zits. You name it honey will kill the bacteria.

    • If you are allergic to penicillin, like I am, you could try cephalexin, which is a bit different and has only 30% cross-reactivity with Pen.-allergic people.
      If we are talking zombie apocalypse, then it is likely the uninformed will swipe all of the Advil and Aleve and maybe some common antibiotics.
      But they might skip the Keflex, or the stuff that doesn’t look like it will get you high.
      Keflex is a two-tone, institution-green gelcap, clearly labeled as Keflex with a 500 or 250 to indicate dosage.
      The most important thing to remember about taking ANY antibiotic is that doing so is a double-edged sword. Not due to any potential side-effects, but due to the chance that you will make yourself vulnerable to more aggressive, antibiotic-resistant strains of other bacteria or even the same bacteria if you fail to take a full course, which is usually as long as it takes to heal the infection.
      30 500mg pills three times a day for ten days is the typical antibiotic regimen for the average adult.
      If you do not have access to a full regimen, and it is a life-or-death situation, then take the risk.
      Just be aware of potential negative consequences.

    • I would suggest you purchase a variety of antibiotics from your online pet care. They are no different in manufacturing or dose, and is safer than trying to grow mold. You don’t need a prescription, they cost about 30 bucks a bottle. Keep a supply and watch expiration dates. They have amoxicilian, penicillin, clindamycin and others. Obviously this only if you have a total collapse of the healthcare system and society and the illness dictates taking antibiotics.

    • Your screwed… not for nothing but just read the article from now and and dont ask stupid shlt. .. this is not designer meds, its like a last ditch effort that can save a life… maybe you want a bottle and some capsules too when your stuck out in the woods hoping you dont die… Do a search for home made birth control, better article for you…

  1. Grammar is awful! Words doubled up or improperly used and autocorrect changed the entire word! Proper writing is going by the wayside!

  2. This is incredibly dangerous and should not be attempted by anyone. This is leftover information from the 1940s. Only one species, Penicillium chrysogenum, produces penicillin, and only about 10% of the strains of that species produce it. Many other Penicillium species are more common and produce mycotoxins. For example, the one shown on the orange, Penicillium digitatum, produces a neurotoxin. Many other molds can also grow on bread and oranges (and other foods), and many of these also produce toxins. Please remove this dangerous information.
    —A Mycology professor

    • I agree totally. The article implies bread and oranges natural have this mold when it actually comes from the environment. Not every green mold is pencillin ( aspergillus would be more likely) and then what you said about gram pos vs gram neg although gram pos (Staph) is most likely. If there is no other option this can be tried but the honey may be the best bet.

    • Thanks Tom, I was just coming here to say the same thing! As a mycologist, reading that article made my skin crawl, and the lack of real information could get someone hurt.

  3. There are a lot of herbs and spices that are very good antimicrobials. Prevention is the most important thing. You can use essential oils diluted with sterile water. Good ones are lavender and thyme. Always use diluted essential oils and you should always check for allergic reactions before applying large amounts especially over a wound. Poultices can be made with oils or whole herbs. Lots of information on line as to how to do this properly.
    Calendula is an excellent antibiotic for almost any skin condition. Garlic is one of the strongest natural antibiotics. Good for internal and external use. Clove tea can be used for internal problems as well. Yarrow, cranberry and corn silk (organic and non-gmo of course) are great for urinary tract infections.
    Some good antivirals are lemon balm, ginger, oregano and elderberry.
    Thyme is also antifungal, good for athletes foot for example.
    Lots of good information on line about herbal remedies. These are only a very few examples of the many herbs out there with medicinal uses.

    • Yeah, I grow loads of thyme, and other herbs it’s great stuff along with ginger and garlic, make a tea out of that with some lemon and honey.

  4. Common Bread Mold Fungus is Rhizopus stolonifer. This is the first time I had an opportunity to use that factoid since having to commit it to memory in 7th Grade Biology, 40-some years ago!! But, I think you are on track with orange mold if you’re trying for penicillin… except, there are many strains and other meanie-greeie fungus that also grow on oranges. I think I would stick with oil of oregano, garlic, and other natural remedies. You are liable to do far more damage than good with this homemade approach! 😉

  5. For a college project in one of my biology classes, a friend and I recreated a few of the first penicillin experiments. We were fortunate to find that our homemade penicillin reduced staph aureus by 30% and E. Coli by 20%. Not bad for using old medicine against new strains of bacteria.

  6. Self-medication is a terrible idea, especially in terms of antibiotics. We don’t have that many different antibiotics, and when bacteria develop resistance because of a faulty or exaggerated use, it’s an irreversible process. You are attacking the community with your selfish use of antibiotics.

    Besides, how do you know the dose is the correct one? And what about allergical reactions?

    DON’T follow this advice.

  7. This is incredibly dangerous. You have no idea what mold you have simply by eyeballing it. You need to to be able to identify and test the molds. These require sterile petri dishes and known test cultures. Growing molds in a sterile lab setting requires very specific sterile procedures, even breathing on a dish can contaminate it. This type of project could kill you especially since you would already have a weakened immune system. Do don’t try this.

  8. This is just a bad idea. Don’t mess around with infections, doing so can seriously kill you. An infection can turn septic and kill you dead, travel to your brain and give you meningitis and kill you dead. Or it can travel to many of your other organs and kill you dead. Be smart, if you notice streaking near an infection, swelling, warmth, stiffness…See a doctor immediately.

  9. How you very sure that green mould is penecillium, it might be something else and at that time you may add risk by consuming mycotoxin or other bad staff.

  10. Do you want sepsis? Because this is how you get sepsis.

    Pennicillin isn’t the ONLY green mold. Bacillus is also green.

  11. If you get winged in a zombie apocalypse scenario, your best bet is to cauterize. Or, you know, wait three weeks for mystery mold to grow on your precious food supply (where are you getting bread and oranges in the apocalypse?) and hope for the best when you chug it.

  12. Hi I just wanted to say that your information is timely. As societies are now being manipulated into a final collapse all information regarding survival will become important. My concern now is actually how much time do we have? We need some of the crystal ball readers to come forward with their insights and predictions.

  13. Maybe you should proof your articles before you post them. It looks like a 10 year old asian boy who only speaks broken English wrote that shit. But…. it’s a cool article non the less.

  14. I would advise against trying to grow your own penicillium molds…at least from breads. Although you may think what you’ve grown is penicillium there is a high chance it could be other types of similar looking molds that can be hazardous when ingested or even inhaled such as the Mucor group of molds that can grow on breads and rotting vegetable matter that if inhaled can be worse than the flesh eating virus. Basically guys, you shouldn’t be fucking around with anti-biotics from self-diagnosing yourself online. This is how we ended up with anti-biotic resistance (from people taking anti-biotics when they didn’t need them and building bacterial intolerance to the antibiotics). Avoid making this shit on your own unless you want to risk YOUR FACE –> Google Mucor Eat’s Man’s Face. Just kind warnings from a microbiologist in uni that doesn’t want people dying because of “make this @ home” articles like this x.x.

  15. My fear is my Dad which was a diabetic that he let get out of control. He was exposed to mold. At first we thought maybe it was spores in the soil but he hasn’t been outside. We did find molded bread in his house. He contracted mucormycosis. After 3 hospitals & 1 being 5 hrs away the mold went in to his brain even after several scrapings & surgeries in the sinus area & mouth. I took him home where he only lasted another 2 weeks. This took him within about 2 months total. I’m telling the suffering, pain & other issues it brought on I’d probably never try this.

    • Thank u,”MG,’,with Dr.Government now a days,,tellin all are doctors what and how much medicine their allowed to prescribe,,,More and more Doc’s in fear of Dr.Government, dea,,,are choosing torture and genocide of the medically ill AS their new prescriptions,,,instead of growing some balls and fighting back,,,Furthermore w/10,000 deductibles, out of pockets,,whilst the rich and the federal government gets insurance coverage w/no out of pocket monies,,,the more we can figure out on our own,,,,the better!!!!MARY

    • This is not ok. This article should be banned. If you have a cut or torn flesh, simple put white or red wine and then rosemery tea. It is a natural antiseptic and it take like what?, 3 minutes to brew? Waiting for mold to grow on a piece of bread or fruit is idiotic. After a few days you can star applying raw honey, which is an antibiotic and that’s it.

  16. As a retired healthcare professional I wouldn’t even try this for a very good reason: You have NO way to see, or regulate the dosage, not to mention the concern for cross contamination of another microbe since you are not in a sterile environment with the equipment (and smarts) to detect other contaminants.

  17. Holy shit… Doctors and undergrads are more afraid of people trying out penecilin growing then Marie Currie was playing with Uranium.
    How about spreading knowledge… Teach people what to avoid and how to distinguish good/bad.
    If people want to do stupid stuff… There are plenty of ways. Btw… I need a good way to weaponize clostridum :p.

  18. Why would you lie to readers on the internet? Can you cite the sources that led you to assert that penicillin has been used for thousands of years becasue the truth that I know is that The “marvellous mould that saves lives,” as TIME put it, was first discovered by Alexander Fleming in 1928, but more than a decade would pass before the first American patient was treated with penicillin on this day, Mar. 14, in 1942.


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